A female is diagnosed with PCOS if she has two of the three criteria (called Rotterdam criteria):
1. Oligomenorrhea (>45 days or <8 menstrual cycles per year) and/or anovulation (no cycle)
2. Hyperandrogenism - Biochemical: Total testosterone, >70 ng/dL, Clinical: Acne, Hirsutism (unwanted hair growth in the face and body), Acanthosis nigricans (velvety black patch around the neck, face and/or in joints)
3. Polycystic ovaries - >12 follicles/eggs (2-9 mm diameter) in each ovary; Ovarian volume >10 cc (in ultrasound scan)
The picture below shows the presence of multiple cysts (immature follicles) in the ovaries as compared to one mature follicle in the normal ovary during the course of a menstrual cycle.